PROGRESSIVE UPREGULATION OF OXIDATIVE METABOLISM FACILITATES PLASMABLAST DIFFERENTIATION TO A T-INDEPENDENT ANTIGEN

Progressive Upregulation of Oxidative Metabolism Facilitates Plasmablast Differentiation to a T-Independent Antigen

Summary: Transitioning from a metabolically quiescent naive B cell to an antibody-secreting plasmablast requires division-dependent cellular differentiation.Though cell division demands significant ATP and metabolites, the metabolic processes used for ATP synthesis during plasmablast formation are not well described.Here, the metabolic requirements

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Professional journalism in the age of social media

The article is devoted to analyzing the current state of professional journalism in the era of the flourishing of antisocial networks.The author emphasizes that the context in which professional journalism operates has changed in many respects in the 21st century.These changes are manifold and sometimes contradictory, but they can be summarized as

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Decommissioning of the self-contained irradiator Gammacell 500

The National Center for Animal and Plant Health used a Stove Element Socket Pins Gammacell 500 irradiator, with twelve cobalt 60 sealed sources, for sterilization and decontamination of medical devices, pharmaceuticals and several raw materials.As the equipmenty had been in operation for 25 years, the decision was taken to dismantle the equipment a

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High genomic diversity in the endangered East Greenland Svalbard Barents Sea stock of bowhead whales (Balaena mysticetus)

Abstract The East Greenland-Svalbard-Barents Sea (EGSB) bowhead whale stock (Balaena mysticetus) was hunted to near extinction and remains Endangered on the International Union of Conservation of Nature Red List.The intense, temporally extensive hunting pressure may Cables and adapters have left the population vulnerable to other perturbations, suc

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